Two appetite suppressants - sibutramine (Reductil) and rimonabant (Acomplia) - were taken off the UK market in recent years. Both went through clinical trials but once people widely began using them, dangerous side-effects were reported. Side effects from one drug included making the people taking them feel suicidal, while another drug increased the chances of having a non-fatal heart attack or stroke.
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The only diet medication which is currently licensed in the UK as safe and effective is orlistat, which is a lipase inhibitor. This means that it reduces the amount of energy that you take in from the fat contained in foods that you eat, and the undigested fat is passed along with your faeces. It doesn’t suppress the appetite, but instead works by preventing up to a third of the fat that you eat from being absorbed by the body.
Not much of a coffee drinker? Tea is also a natural diuretic, and types of herbal tea such as dandelion or fennel root can also lend a hand. In fact: When a recent study compared the metabolic effect of green tea (in extract) with that of a placebo, researchers found that the green-tea drinkers burned about 70 additional calories in a 24-hour period.
When it comes to appetite, we have three separate studies all showing benefits of 5-HTP supplementation in obese and prediabetic patients (people who were experiencing early symptoms of diabetes). It should be noted that these studies were all conducted by the same research group, although one other study did note some benefit in women who were just overweight.